FRONTLINE Spot On Flea & Tick Treatment Dog L 20-40kg

Protect your dog from annoying parasites! With FRONTLINE Spot-on against ticks, fleas and biting lice.

FRONTLINE Spot-on offers many advantages:
Reliable protection: Ticks are killed within 48 hours and adult fleas within 24 hours.

Works on contact: Parasites do not ingest the active ingredient by sucking blood, but already on
contact with the animal. Ticks are killed within 48 hours and adult fleas within 24 hours.

Well tolerated: FRONTLINE Spot-on is suitable for puppies weighing 2kg and over, as well as for pregnant and lactating bitches!

Easy to use: The active ingredient is simply applied to the skin on the back of the neck with a pipette.

How does FRONTLINE work?
After application, the active ingredient in FRONTLINE Spot-on spreads over the entire body surface and is stored in the sebaceous glands for 4 weeks. The active ingredient therefore does not penetrate the body. If ticks, fleas or biting lice come into contact with the skin or fur, they are reliably killed within 1-2 days. Contact with the animal is therefore sufficient, and the parasites do not need to bite to be killed.

How quickly does FRONTLINE Spot-on work?**

• Fleas: 98-100% are killed within 24 hours
• Ticks: over 90% of ticks die within 48 hours

How is FRONTLINE Spot-on used?
Applying FRONTLINE Spot-on is very easy - the active ingredient solution is applied directly to the skin using a pipette:

• Take a pipette out of the packaging.
• Hold the pipette tip upright, tap the tip briefly with your finger (so that the entire solution is in the lower part of the pipette) and snap it off at the perforated point.
• Part the animal's fur between the shoulder blades until you can see the skin.
• Place the tip of the pipette directly on the skin there and apply the active ingredient solution completely to the skin. Empty the pipette completely by squeezing it several times.

The active ingredient then spreads over the entire body surface of the animal within 1-2 days.

Please note:

• The natural skin condition of the animal is the optimal basis for the distribution and storage of the active ingredient solution. However, intensive bathing before or after treatment (within 48 hours) can impair distribution. FRONTLINE products are waterproof after the distribution period.
• For dogs, also pay attention to the pipette size according to weight. Too low a dosage can impair the success of the treatment. FRONTLINE® products are available for cats and dogs, species-appropriate and in optimally matched pipette sizes.
• For the success of the treatment, it is also important that all dogs and cats living in the household are treated simultaneously and regularly. Untreated animals - both cats and dogs - can re-infect others, especially in the case of flea infestation.
• In the case of flea infestation, it is also very important to free the environment from fleas. Otherwise, your pet can be re-infested again and again. To do this, you should vacuum daily and very thoroughly (including in corners and edges), wash blankets, textiles, toys, etc. at a minimum of 60 degrees, and use products for environmental treatment.
• Important: Under no circumstances should FRONTLINE products be used on rabbits and other small animals!

How often should FRONTLINE Spot-on be used?
Only if there is a continuously sufficient amount of active ingredient can an effect without a protection gap be achieved. FRONTLINE products should be used monthly. Flea infestation is not only a problem in summer and autumn, but also in winter. In heated homes, fleas also feel comfortable in the cold season. Therefore, we recommend year-round preventive treatment, especially for indoor pets.

Which active ingredient is contained in FRONTLINE Spot-on and how does it work?
The active ingredient contained in FRONTLINE Spot-on is Fipronil. Fipronil is an active ingredient that disrupts the nerve transmission in insects (e.g., fleas) and arachnids (e.g., ticks), causing the parasites to die. The active ingredient works on invertebrates (arachnids and insects) and not on mammals such as dogs or humans. Within 1-2 days after application, the active ingredient spreads over the superficial, fat-rich skin layer of the entire body. Fipronil is fat-soluble and is stored in the sebaceous glands. From there, the active ingredient is continuously released with sebum onto the skin and into the fur.

Mandatory text:
Frontline® Spot-on Dog S, M, L, solution for topical application to the skin, for dogs.
Frontline® Spot-on Cat, solution for topical application to the skin, for cats.
Indications: Dog: For the treatment of dogs with a body weight of 2 kg to 10 kg (S), over 10 kg to 20 kg (M), over 20 kg to 40 kg (L) against flea, tick and biting lice infestation. Killing of fleas (Ctenocephalides spp.). Cat: For the treatment of cats against flea, tick and biting lice infestation. Killing of fleas (Ctenocephalides spp.). The insecticidal efficacy against adult fleas is maintained for 8 weeks (Dog), or 4 weeks (Cat). Killing of ticks (Ixodes ricinus, Dermacentes variabilis, Rhipicephalus sanguineus). The acaricidal efficacy against ticks lasts up to 4 weeks (Dog), or 2 weeks (Cat, according to experimental studies). Killing of biting lice (Dog: Trichodectes canis, Cat: Felicola subrostratus). For the therapy and control of flea allergy dermatitis (FAD). [Oct 2017]

This product is a veterinary medicine. For information on application, possible side effects and undesirable effects, please read the package insert or consult your veterinarian or pharmacist.

Sources:
**Fipronil eliminates fleas within 24 hours and ticks as well as biting lice within 48 hours of contact. Studies have shown a success rate of 95-100%: Hunter et al.: World Veterinary Congress (Proceedings), 1999, Lyon; Postal et al.: Proceedings of the 4th International Symposium on Ectoparasites, 1997, Riverside, California.